Epsin-1 (EPN1)
Homo sapiens — UniProt Q9Y6I3
Data last refreshed: (UniProt release unknown)
Key facts
Epsin-1 (EPN1) is a protein from Homo sapiens identified by UniProt accession Q9Y6I3, 576 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: Q9Y6I3; gene symbol EPN1.
- Organism: Homo sapiens.
- Length: 576 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, lung adenocarcinoma and high density lipoprotein cholesterol measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Epsin-1 |
|---|---|
| UniProt accession | Q9Y6I3 |
| Gene | EPN1 |
| Organism | Homo sapiens |
| Length | 576 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.33
- lung adenocarcinoma · score 0.23
- high density lipoprotein cholesterol measurement · score 0.07
- atherosclerosis · score 0.01
- juvenile dermatomyositis · score 0.01
- neoplasm · score 0.01
- adenocarcinoma · score 0.01
- prostate carcinoma · score 0.01
- prostatitis · score 0.01
- colon adenoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6I3-F1 | alphafold | PREDICTED | 63.84 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6I3.
Amino-acid sequence (576 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with EPN1?
The strongest Open Targets associations for EPN1 are neurodegenerative disease, lung adenocarcinoma, high density lipoprotein cholesterol measurement, atherosclerosis and juvenile dermatomyositis.
How long is the EPN1 protein?
The Homo sapiens EPN1 protein (UniProt Q9Y6I3) is 576 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6I3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6I3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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