WD repeat and SOCS box-containing protein 1 (WSB1)
Homo sapiens — UniProt Q9Y6I7
Data last refreshed: (UniProt release unknown)
Key facts
WD repeat and SOCS box-containing protein 1 (WSB1) is a protein from Homo sapiens identified by UniProt accession Q9Y6I7, 421 residues long. MolForge cross-references it against 0 known binders and 64 disease associations.
- UniProt accession: Q9Y6I7; gene symbol WSB1.
- Organism: Homo sapiens.
- Length: 421 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, body height and birth weight.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | WD repeat and SOCS box-containing protein 1 |
|---|---|
| UniProt accession | Q9Y6I7 |
| Gene | WSB1 |
| Organism | Homo sapiens |
| Length | 421 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (64)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- body height · score 0.41
- birth weight · score 0.36
- hemangioma · score 0.29
- lymphangioma · score 0.29
- chronic myelogenous leukemia · score 0.22
- hepatocellular carcinoma · score 0.08
- cancer · score 0.06
- insulin resistance · score 0.06
- neutrophil count · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6I7-F1 | alphafold | PREDICTED | 84.56 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6I7.
Amino-acid sequence (421 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with WSB1?
The strongest Open Targets associations for WSB1 are neurodegenerative disease, body height, birth weight, hemangioma and lymphangioma.
How long is the WSB1 protein?
The Homo sapiens WSB1 protein (UniProt Q9Y6I7) is 421 amino acids long.
Browse: Targets: W · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6I7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6I7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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