Peroxisomal membrane protein 4 (PXMP4)
Homo sapiens — UniProt Q9Y6I8
Data last refreshed: (UniProt release unknown)
Key facts
Peroxisomal membrane protein 4 (PXMP4) is a protein from Homo sapiens identified by UniProt accession Q9Y6I8, 212 residues long. MolForge cross-references it against 0 known binders and 46 disease associations.
- UniProt accession: Q9Y6I8; gene symbol PXMP4.
- Organism: Homo sapiens.
- Length: 212 amino acids.
- Top disease associations (Open Targets): sex hormone-binding globulin measurement, forced expiratory volume and triglyceride measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Peroxisomal membrane protein 4 |
|---|---|
| UniProt accession | Q9Y6I8 |
| Gene | PXMP4 |
| Organism | Homo sapiens |
| Length | 212 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (46)
Diseases linked to this target (Open Targets).
- sex hormone-binding globulin measurement · score 0.38
- forced expiratory volume · score 0.28
- triglyceride measurement · score 0.28
- body height · score 0.28
- serum alanine aminotransferase measurement · score 0.23
- serum albumin measurement · score 0.22
- lean body mass · score 0.21
- serum gamma-glutamyl transferase measurement · score 0.20
- mean platelet volume · score 0.20
- aspartate aminotransferase to alanine aminotransferase ratio · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6I8-F1 | alphafold | PREDICTED | 91.82 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6I8.
Amino-acid sequence (212 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PXMP4?
The strongest Open Targets associations for PXMP4 are sex hormone-binding globulin measurement, forced expiratory volume, triglyceride measurement, body height and serum alanine aminotransferase measurement.
How long is the PXMP4 protein?
The Homo sapiens PXMP4 protein (UniProt Q9Y6I8) is 212 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6I8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6I8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.