TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (TAF6L)
Homo sapiens — UniProt Q9Y6J9
Data last refreshed: (UniProt release unknown)
Key facts
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (TAF6L) is a protein from Homo sapiens identified by UniProt accession Q9Y6J9, 622 residues long. MolForge cross-references it against 0 known binders and 3 disease associations.
- UniProt accession: Q9Y6J9; gene symbol TAF6L.
- Organism: Homo sapiens.
- Length: 622 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, mean reticulocyte volume and COVID-19.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L |
|---|---|
| UniProt accession | Q9Y6J9 |
| Gene | TAF6L |
| Organism | Homo sapiens |
| Length | 622 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (3)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- mean reticulocyte volume · score 0.13
- COVID-19 · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6J9-F1 | alphafold | PREDICTED | 67.89 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6J9.
Amino-acid sequence (622 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TAF6L?
The strongest Open Targets associations for TAF6L are neurodegenerative disease, mean reticulocyte volume and COVID-19.
How long is the TAF6L protein?
The Homo sapiens TAF6L protein (UniProt Q9Y6J9) is 622 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6J9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6J9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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