Adenylate kinase isoenzyme 5 (AK5)
Homo sapiens — UniProt Q9Y6K8
Data last refreshed: (UniProt release unknown)
Key facts
Adenylate kinase isoenzyme 5 (AK5) is a protein from Homo sapiens identified by UniProt accession Q9Y6K8, 562 residues long. MolForge cross-references it against 0 known binders and 92 disease associations.
- UniProt accession: Q9Y6K8; gene symbol AK5.
- Organism: Homo sapiens.
- Length: 562 amino acids.
- Top disease associations (Open Targets): chronotype measurement, circadian rhythm and self reported educational attainment.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Adenylate kinase isoenzyme 5 |
|---|---|
| UniProt accession | Q9Y6K8 |
| Gene | AK5 |
| Organism | Homo sapiens |
| Length | 562 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (92)
Diseases linked to this target (Open Targets).
- chronotype measurement · score 0.43
- circadian rhythm · score 0.40
- self reported educational attainment · score 0.39
- body mass index · score 0.39
- body fat percentage · score 0.35
- eosinophil count · score 0.34
- mean reticulocyte volume · score 0.32
- albuminuria · score 0.28
- urinary albumin to creatinine ratio · score 0.28
- eosinophil percentage of leukocytes · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6K8-F1 | alphafold | PREDICTED | 78.32 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6K8.
Amino-acid sequence (562 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with AK5?
The strongest Open Targets associations for AK5 are chronotype measurement, circadian rhythm, self reported educational attainment, body mass index and body fat percentage.
How long is the AK5 protein?
The Homo sapiens AK5 protein (UniProt Q9Y6K8) is 562 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6K8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6K8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.