Casein kinase I isoform gamma-3 (CSNK1G3)
Homo sapiens — UniProt Q9Y6M4
Data last refreshed: (UniProt release unknown)
Key facts
Casein kinase I isoform gamma-3 (CSNK1G3) is a protein from Homo sapiens identified by UniProt accession Q9Y6M4, 447 residues long. MolForge cross-references it against 2 known binders and 43 disease associations.
- UniProt accession: Q9Y6M4; gene symbol CSNK1G3.
- Organism: Homo sapiens.
- Length: 447 amino acids.
- Top disease associations (Open Targets): low density lipoprotein cholesterol measurement, Red cell distribution width and total cholesterol measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Casein kinase I isoform gamma-3 |
|---|---|
| UniProt accession | Q9Y6M4 |
| Gene | CSNK1G3 |
| Organism | Homo sapiens |
| Length | 447 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (43)
Diseases linked to this target (Open Targets).
- low density lipoprotein cholesterol measurement · score 0.40
- Red cell distribution width · score 0.38
- total cholesterol measurement · score 0.37
- bilirubin measurement · score 0.35
- diastolic blood pressure · score 0.34
- heel bone mineral density · score 0.33
- apolipoprotein B measurement · score 0.32
- serum albumin measurement · score 0.32
- serum gamma-glutamyl transferase measurement · score 0.27
- pulse pressure measurement · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6M4-F1 | alphafold | PREDICTED | 76.02 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6M4.
Amino-acid sequence (447 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CSNK1G3?
The strongest Open Targets associations for CSNK1G3 are low density lipoprotein cholesterol measurement, Red cell distribution width, total cholesterol measurement, bilirubin measurement and diastolic blood pressure.
How long is the CSNK1G3 protein?
The Homo sapiens CSNK1G3 protein (UniProt Q9Y6M4) is 447 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6M4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6M4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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