Proton-coupled zinc antiporter SLC30A1 (SLC30A1)
Homo sapiens — UniProt Q9Y6M5
Data last refreshed: (UniProt release unknown)
Key facts
Proton-coupled zinc antiporter SLC30A1 (SLC30A1) is a protein from Homo sapiens identified by UniProt accession Q9Y6M5, 507 residues long. MolForge cross-references it against 0 known binders and 107 disease associations.
- UniProt accession: Q9Y6M5; gene symbol SLC30A1.
- Organism: Homo sapiens.
- Length: 507 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, appendicular lean mass and mean corpuscular hemoglobin concentration.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Proton-coupled zinc antiporter SLC30A1 |
|---|---|
| UniProt accession | Q9Y6M5 |
| Gene | SLC30A1 |
| Organism | Homo sapiens |
| Length | 507 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (107)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.46
- appendicular lean mass · score 0.34
- mean corpuscular hemoglobin concentration · score 0.31
- mean corpuscular hemoglobin · score 0.26
- serum alanine aminotransferase measurement · score 0.26
- self reported educational attainment · score 0.25
- nevus count · score 0.25
- alkaline phosphatase measurement · score 0.20
- Red cell distribution width · score 0.19
- platelet component distribution width · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6M5-F1 | alphafold | PREDICTED | 67.40 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6M5.
Amino-acid sequence (507 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC30A1?
The strongest Open Targets associations for SLC30A1 are neurodegenerative disease, appendicular lean mass, mean corpuscular hemoglobin concentration, mean corpuscular hemoglobin and serum alanine aminotransferase measurement.
How long is the SLC30A1 protein?
The Homo sapiens SLC30A1 protein (UniProt Q9Y6M5) is 507 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6M5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6M5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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