Sodium bicarbonate cotransporter 3 (SLC4A7)
Homo sapiens — UniProt Q9Y6M7
Data last refreshed: (UniProt release unknown)
Key facts
Sodium bicarbonate cotransporter 3 (SLC4A7) is a protein from Homo sapiens identified by UniProt accession Q9Y6M7, 1214 residues long. MolForge cross-references it against 0 known binders and 273 disease associations.
- UniProt accession: Q9Y6M7; gene symbol SLC4A7.
- Organism: Homo sapiens.
- Length: 1214 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): diastolic blood pressure, systolic blood pressure and pulse pressure measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sodium bicarbonate cotransporter 3 |
|---|---|
| UniProt accession | Q9Y6M7 |
| Gene | SLC4A7 |
| Organism | Homo sapiens |
| Length | 1214 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (273)
Diseases linked to this target (Open Targets).
- diastolic blood pressure · score 0.48
- systolic blood pressure · score 0.48
- pulse pressure measurement · score 0.45
- mean arterial pressure · score 0.44
- alcohol drinking · score 0.44
- smoking status measurement · score 0.44
- hypertension · score 0.43
- platelet count · score 0.41
- lymphocyte count · score 0.38
- appendicular lean mass · score 0.38
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6M7-F1 | alphafold | PREDICTED | 67.53 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6M7.
Amino-acid sequence (1214 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC4A7?
The strongest Open Targets associations for SLC4A7 are diastolic blood pressure, systolic blood pressure, pulse pressure measurement, mean arterial pressure and alcohol drinking.
How long is the SLC4A7 protein?
The Homo sapiens SLC4A7 protein (UniProt Q9Y6M7) is 1214 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6M7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6M7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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