NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (NDUFB9)
Homo sapiens — UniProt Q9Y6M9
Data last refreshed: (UniProt release unknown)
Key facts
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (NDUFB9) is a protein from Homo sapiens identified by UniProt accession Q9Y6M9, 179 residues long. MolForge cross-references it against 0 known binders and 248 disease associations.
- UniProt accession: Q9Y6M9; gene symbol NDUFB9.
- Organism: Homo sapiens.
- Length: 179 amino acids.
- Top disease associations (Open Targets): type 2 diabetes mellitus, polycystic ovary syndrome and diabetes mellitus.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 |
|---|---|
| UniProt accession | Q9Y6M9 |
| Gene | NDUFB9 |
| Organism | Homo sapiens |
| Length | 179 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (248)
Diseases linked to this target (Open Targets).
- type 2 diabetes mellitus · score 0.61
- polycystic ovary syndrome · score 0.60
- diabetes mellitus · score 0.60
- type 1 diabetes mellitus · score 0.58
- gestational diabetes · score 0.58
- neurodegenerative disease · score 0.57
- obesity · score 0.57
- prediabetes syndrome · score 0.56
- schizophrenia · score 0.55
- insulin resistance · score 0.55
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6M9-F1 | alphafold | PREDICTED | 95.74 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6M9.
Amino-acid sequence (179 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NDUFB9?
The strongest Open Targets associations for NDUFB9 are type 2 diabetes mellitus, polycystic ovary syndrome, diabetes mellitus, type 1 diabetes mellitus and gestational diabetes.
How long is the NDUFB9 protein?
The Homo sapiens NDUFB9 protein (UniProt Q9Y6M9) is 179 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6M9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6M9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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