Cytochrome c oxidase assembly protein COX11, mitochondrial (COX11)
Homo sapiens — UniProt Q9Y6N1
Data last refreshed: (UniProt release unknown)
Key facts
Cytochrome c oxidase assembly protein COX11, mitochondrial (COX11) is a protein from Homo sapiens identified by UniProt accession Q9Y6N1, 276 residues long. MolForge cross-references it against 0 known binders and 65 disease associations.
- UniProt accession: Q9Y6N1; gene symbol COX11.
- Organism: Homo sapiens.
- Length: 276 amino acids.
- Top disease associations (Open Targets): mitochondrial complex IV deficiency, nuclear type 23, neurodegenerative disease and breast adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cytochrome c oxidase assembly protein COX11, mitochondrial |
|---|---|
| UniProt accession | Q9Y6N1 |
| Gene | COX11 |
| Organism | Homo sapiens |
| Length | 276 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (65)
Diseases linked to this target (Open Targets).
- mitochondrial complex IV deficiency, nuclear type 23 · score 0.66
- neurodegenerative disease · score 0.53
- breast adenocarcinoma · score 0.23
- lung adenocarcinoma · score 0.19
- ovarian cancer · score 0.18
- squamous cell lung carcinoma · score 0.18
- head and neck squamous cell carcinoma · score 0.18
- platelet count · score 0.18
- breast carcinoma · score 0.17
- gastric adenocarcinoma · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6N1-F1 | alphafold | PREDICTED | 74.21 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6N1.
Amino-acid sequence (276 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with COX11?
The strongest Open Targets associations for COX11 are mitochondrial complex IV deficiency, nuclear type 23, neurodegenerative disease, breast adenocarcinoma, lung adenocarcinoma and ovarian cancer.
How long is the COX11 protein?
The Homo sapiens COX11 protein (UniProt Q9Y6N1) is 276 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6N1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6N1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.