Sulfide:quinone oxidoreductase, mitochondrial (SQOR)
Homo sapiens — UniProt Q9Y6N5
Data last refreshed: (UniProt release unknown)
Key facts
Sulfide:quinone oxidoreductase, mitochondrial (SQOR) is a protein from Homo sapiens identified by UniProt accession Q9Y6N5, 450 residues long. MolForge cross-references it against 2 known binders and 57 disease associations.
- UniProt accession: Q9Y6N5; gene symbol SQOR.
- Organism: Homo sapiens.
- Length: 450 amino acids.
- Top disease associations (Open Targets): sulfide quinone oxidoreductase deficiency, Leigh syndrome and health study participation.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sulfide:quinone oxidoreductase, mitochondrial |
|---|---|
| UniProt accession | Q9Y6N5 |
| Gene | SQOR |
| Organism | Homo sapiens |
| Length | 450 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (57)
Diseases linked to this target (Open Targets).
- sulfide quinone oxidoreductase deficiency · score 0.51
- Leigh syndrome · score 0.47
- health study participation · score 0.08
- acute kidney failure · score 0.07
- Osteoporosis · score 0.03
- Acute kidney injury · score 0.02
- Crohn's disease · score 0.01
- neoplasm · score 0.01
- lung carcinoma · score 0.01
- Cerebral ischemia · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6N5-F1 | alphafold | PREDICTED | 92.99 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6N5.
Amino-acid sequence (450 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SQOR?
The strongest Open Targets associations for SQOR are sulfide quinone oxidoreductase deficiency, Leigh syndrome, health study participation, acute kidney failure and Osteoporosis.
How long is the SQOR protein?
The Homo sapiens SQOR protein (UniProt Q9Y6N5) is 450 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6N5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6N5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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