Cadherin-10 (CDH10)
Homo sapiens — UniProt Q9Y6N8
Data last refreshed: (UniProt release unknown)
Key facts
Cadherin-10 (CDH10) is a protein from Homo sapiens identified by UniProt accession Q9Y6N8, 788 residues long. MolForge cross-references it against 0 known binders and 200 disease associations.
- UniProt accession: Q9Y6N8; gene symbol CDH10.
- Organism: Homo sapiens.
- Length: 788 amino acids.
- Top disease associations (Open Targets): neurofibrillary tangles measurement, sphingomyelin measurement and DNA methylation.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cadherin-10 |
|---|---|
| UniProt accession | Q9Y6N8 |
| Gene | CDH10 |
| Organism | Homo sapiens |
| Length | 788 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (200)
Diseases linked to this target (Open Targets).
- neurofibrillary tangles measurement · score 0.40
- sphingomyelin measurement · score 0.36
- DNA methylation · score 0.28
- polycystic ovary syndrome · score 0.27
- breast adenocarcinoma · score 0.26
- medulloblastoma · score 0.25
- endometrial cancer · score 0.25
- head and neck squamous cell carcinoma · score 0.23
- lung adenocarcinoma · score 0.23
- squamous cell lung carcinoma · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6N8-F1 | alphafold | PREDICTED | 78.37 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6N8.
Amino-acid sequence (788 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CDH10?
The strongest Open Targets associations for CDH10 are neurofibrillary tangles measurement, sphingomyelin measurement, DNA methylation, polycystic ovary syndrome and breast adenocarcinoma.
How long is the CDH10 protein?
The Homo sapiens CDH10 protein (UniProt Q9Y6N8) is 788 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6N8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6N8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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