Calpain-6 (CAPN6)
Homo sapiens — UniProt Q9Y6Q1
Data last refreshed: (UniProt release unknown)
Key facts
Calpain-6 (CAPN6) is a protein from Homo sapiens identified by UniProt accession Q9Y6Q1, 641 residues long. MolForge cross-references it against 0 known binders and 64 disease associations.
- UniProt accession: Q9Y6Q1; gene symbol CAPN6.
- Organism: Homo sapiens.
- Length: 641 amino acids.
- Top disease associations (Open Targets): breast adenocarcinoma, body height and prostate carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Calpain-6 |
|---|---|
| UniProt accession | Q9Y6Q1 |
| Gene | CAPN6 |
| Organism | Homo sapiens |
| Length | 641 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (64)
Diseases linked to this target (Open Targets).
- breast adenocarcinoma · score 0.22
- body height · score 0.22
- prostate carcinoma · score 0.11
- prostate cancer · score 0.11
- Familial prostate cancer · score 0.11
- head and neck squamous cell carcinoma · score 0.08
- neoplasm · score 0.07
- chronic kidney disease · score 0.05
- breast carcinoma · score 0.04
- macroglossia · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6Q1-F1 | alphafold | PREDICTED | 91.42 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6Q1.
Amino-acid sequence (641 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CAPN6?
The strongest Open Targets associations for CAPN6 are breast adenocarcinoma, body height, prostate carcinoma, prostate cancer and Familial prostate cancer.
How long is the CAPN6 protein?
The Homo sapiens CAPN6 protein (UniProt Q9Y6Q1) is 641 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6Q1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6Q1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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