Stonin-1 (STON1)
Homo sapiens — UniProt Q9Y6Q2
Data last refreshed: (UniProt release unknown)
Key facts
Stonin-1 (STON1) is a protein from Homo sapiens identified by UniProt accession Q9Y6Q2, 735 residues long. MolForge cross-references it against 0 known binders and 62 disease associations.
- UniProt accession: Q9Y6Q2; gene symbol STON1.
- Organism: Homo sapiens.
- Length: 735 amino acids.
- Top disease associations (Open Targets): reticulocyte count, serum non-albumin protein measurement and retinal layer thickness measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Stonin-1 |
|---|---|
| UniProt accession | Q9Y6Q2 |
| Gene | STON1 |
| Organism | Homo sapiens |
| Length | 735 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (62)
Diseases linked to this target (Open Targets).
- reticulocyte count · score 0.38
- serum non-albumin protein measurement · score 0.29
- retinal layer thickness measurement · score 0.28
- risk-taking behaviour · score 0.28
- retinal nerve fibre layer thickness measurement · score 0.27
- total blood protein measurement · score 0.27
- brain volume measurement · score 0.27
- aspartate aminotransferase measurement · score 0.26
- apolipoprotein A 1 measurement · score 0.25
- gut microbiome measurement · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6Q2-F1 | alphafold | PREDICTED | 64.78 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6Q2.
Amino-acid sequence (735 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with STON1?
The strongest Open Targets associations for STON1 are reticulocyte count, serum non-albumin protein measurement, retinal layer thickness measurement, risk-taking behaviour and retinal nerve fibre layer thickness measurement.
How long is the STON1 protein?
The Homo sapiens STON1 protein (UniProt Q9Y6Q2) is 735 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6Q2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6Q2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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