Zinc finger protein 37 homolog (ZFP37)
Homo sapiens — UniProt Q9Y6Q3
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 37 homolog (ZFP37) is a protein from Homo sapiens identified by UniProt accession Q9Y6Q3, 630 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.
- UniProt accession: Q9Y6Q3; gene symbol ZFP37.
- Organism: Homo sapiens.
- Length: 630 amino acids.
- Top disease associations (Open Targets): neurofibrillary tangles measurement, PHF-tau measurement and blood protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 37 homolog |
|---|---|
| UniProt accession | Q9Y6Q3 |
| Gene | ZFP37 |
| Organism | Homo sapiens |
| Length | 630 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (17)
Diseases linked to this target (Open Targets).
- neurofibrillary tangles measurement · score 0.22
- PHF-tau measurement · score 0.22
- blood protein measurement · score 0.15
- myeloid white cell count · score 0.02
- neutrophil count · score 0.02
- erythrocyte count · score 0.02
- neutrophil percentage of leukocytes · score 0.02
- neoplasm · score 0.02
- cancer · score 0.02
- lung carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6Q3-F1 | alphafold | PREDICTED | 67.04 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6Q3.
Amino-acid sequence (630 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZFP37?
The strongest Open Targets associations for ZFP37 are neurofibrillary tangles measurement, PHF-tau measurement, blood protein measurement, myeloid white cell count and neutrophil count.
How long is the ZFP37 protein?
The Homo sapiens ZFP37 protein (UniProt Q9Y6Q3) is 630 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6Q3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6Q3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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