Zinc finger protein 780B (ZNF780B)
Homo sapiens — UniProt Q9Y6R6
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 780B (ZNF780B) is a protein from Homo sapiens identified by UniProt accession Q9Y6R6, 833 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.
- UniProt accession: Q9Y6R6; gene symbol ZNF780B.
- Organism: Homo sapiens.
- Length: 833 amino acids.
- Top disease associations (Open Targets): IGA glomerulonephritis, microphthalmia with limb anomalies and hepatocellular carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 780B |
|---|---|
| UniProt accession | Q9Y6R6 |
| Gene | ZNF780B |
| Organism | Homo sapiens |
| Length | 833 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (4)
Diseases linked to this target (Open Targets).
- IGA glomerulonephritis · score 0.01
- microphthalmia with limb anomalies · score 0.00
- hepatocellular carcinoma · score 0.00
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6R6-F1 | alphafold | PREDICTED | 73.17 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6R6.
Amino-acid sequence (833 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF780B?
The strongest Open Targets associations for ZNF780B are IGA glomerulonephritis, microphthalmia with limb anomalies, hepatocellular carcinoma and cancer.
How long is the ZNF780B protein?
The Homo sapiens ZNF780B protein (UniProt Q9Y6R6) is 833 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6R6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6R6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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