RING finger protein 215 (RNF215)
Homo sapiens — UniProt Q9Y6U7
Data last refreshed: (UniProt release unknown)
Key facts
RING finger protein 215 (RNF215) is a protein from Homo sapiens identified by UniProt accession Q9Y6U7, 377 residues long. MolForge cross-references it against 0 known binders and 47 disease associations.
- UniProt accession: Q9Y6U7; gene symbol RNF215.
- Organism: Homo sapiens.
- Length: 377 amino acids.
- Top disease associations (Open Targets): sex hormone-binding globulin measurement, platelet count and white matter microstructure measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | RING finger protein 215 |
|---|---|
| UniProt accession | Q9Y6U7 |
| Gene | RNF215 |
| Organism | Homo sapiens |
| Length | 377 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (47)
Diseases linked to this target (Open Targets).
- sex hormone-binding globulin measurement · score 0.20
- platelet count · score 0.18
- white matter microstructure measurement · score 0.18
- calcium measurement · score 0.17
- total cholesterol measurement · score 0.16
- eosinophil count · score 0.13
- BMI-adjusted waist circumference · score 0.13
- pulse pressure measurement · score 0.12
- HbA1c measurement · score 0.11
- platelet crit · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6U7-F1 | alphafold | PREDICTED | 65.87 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6U7.
Amino-acid sequence (377 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RNF215?
The strongest Open Targets associations for RNF215 are sex hormone-binding globulin measurement, platelet count, white matter microstructure measurement, calcium measurement and total cholesterol measurement.
How long is the RNF215 protein?
The Homo sapiens RNF215 protein (UniProt Q9Y6U7) is 377 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6U7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6U7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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