Calpain-7 (CAPN7)
Homo sapiens — UniProt Q9Y6W3
Data last refreshed: (UniProt release unknown)
Key facts
Calpain-7 (CAPN7) is a protein from Homo sapiens identified by UniProt accession Q9Y6W3, 813 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q9Y6W3; gene symbol CAPN7.
- Organism: Homo sapiens.
- Length: 813 amino acids.
- Top disease associations (Open Targets): breast adenocarcinoma, protein measurement and mean platelet volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Calpain-7 |
|---|---|
| UniProt accession | Q9Y6W3 |
| Gene | CAPN7 |
| Organism | Homo sapiens |
| Length | 813 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- breast adenocarcinoma · score 0.22
- protein measurement · score 0.13
- mean platelet volume · score 0.08
- endometriosis · score 0.03
- Diarrhea · score 0.03
- response to darapladib · score 0.03
- PHF-tau measurement · score 0.02
- systemic scleroderma · score 0.02
- neoplasm · score 0.01
- Infertility · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6W3-F1 | alphafold | PREDICTED | 88.51 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6W3.
Amino-acid sequence (813 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CAPN7?
The strongest Open Targets associations for CAPN7 are breast adenocarcinoma, protein measurement, mean platelet volume, endometriosis and Diarrhea.
How long is the CAPN7 protein?
The Homo sapiens CAPN7 protein (UniProt Q9Y6W3) is 813 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6W3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6W3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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