Actin-binding protein WASF2 (WASF2)
Homo sapiens — UniProt Q9Y6W5
Data last refreshed: (UniProt release unknown)
Key facts
Actin-binding protein WASF2 (WASF2) is a protein from Homo sapiens identified by UniProt accession Q9Y6W5, 498 residues long. MolForge cross-references it against 0 known binders and 96 disease associations.
- UniProt accession: Q9Y6W5; gene symbol WASF2.
- Organism: Homo sapiens.
- Length: 498 amino acids.
- Top disease associations (Open Targets): breast adenocarcinoma, creatinine measurement and systolic blood pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Actin-binding protein WASF2 |
|---|---|
| UniProt accession | Q9Y6W5 |
| Gene | WASF2 |
| Organism | Homo sapiens |
| Length | 498 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (96)
Diseases linked to this target (Open Targets).
- breast adenocarcinoma · score 0.25
- creatinine measurement · score 0.16
- systolic blood pressure · score 0.14
- sitting height measurement · score 0.14
- head and neck squamous cell carcinoma · score 0.12
- blood protein measurement · score 0.12
- neoplasm · score 0.10
- arterial stiffness measurement · score 0.10
- monocyte count · score 0.09
- cancer · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6W5-F1 | alphafold | PREDICTED | 67.56 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6W5.
Amino-acid sequence (498 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with WASF2?
The strongest Open Targets associations for WASF2 are breast adenocarcinoma, creatinine measurement, systolic blood pressure, sitting height measurement and head and neck squamous cell carcinoma.
How long is the WASF2 protein?
The Homo sapiens WASF2 protein (UniProt Q9Y6W5) is 498 amino acids long.
Browse: Targets: W · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6W5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6W5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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