Dual specificity protein phosphatase 10 (DUSP10)
Homo sapiens — UniProt Q9Y6W6
Data last refreshed: (UniProt release unknown)
Key facts
Dual specificity protein phosphatase 10 (DUSP10) is a protein from Homo sapiens identified by UniProt accession Q9Y6W6, 482 residues long. MolForge cross-references it against 0 known binders and 162 disease associations.
- UniProt accession: Q9Y6W6; gene symbol DUSP10.
- Organism: Homo sapiens.
- Length: 482 amino acids.
- Top disease associations (Open Targets): self reported educational attainment, vital capacity and body fat percentage.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Dual specificity protein phosphatase 10 |
|---|---|
| UniProt accession | Q9Y6W6 |
| Gene | DUSP10 |
| Organism | Homo sapiens |
| Length | 482 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (162)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.40
- vital capacity · score 0.38
- body fat percentage · score 0.38
- colorectal cancer · score 0.35
- C-reactive protein measurement · score 0.33
- glioblastoma multiforme · score 0.31
- breast adenocarcinoma · score 0.29
- Varicose veins · score 0.29
- schizophrenia · score 0.28
- intelligence · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6W6-F1 | alphafold | PREDICTED | 69.19 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6W6.
Amino-acid sequence (482 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DUSP10?
The strongest Open Targets associations for DUSP10 are self reported educational attainment, vital capacity, body fat percentage, colorectal cancer and C-reactive protein measurement.
How long is the DUSP10 protein?
The Homo sapiens DUSP10 protein (UniProt Q9Y6W6) is 482 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6W6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6W6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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