Stress-associated endoplasmic reticulum protein 1 (SERP1)
Homo sapiens — UniProt Q9Y6X1
Data last refreshed: (UniProt release unknown)
Key facts
Stress-associated endoplasmic reticulum protein 1 (SERP1) is a protein from Homo sapiens identified by UniProt accession Q9Y6X1, 66 residues long. MolForge cross-references it against 0 known binders and 96 disease associations.
- UniProt accession: Q9Y6X1; gene symbol SERP1.
- Organism: Homo sapiens.
- Length: 66 amino acids.
- Top disease associations (Open Targets): Marinesco-Sjögren syndrome, lymphocyte count and response to vaccine.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Stress-associated endoplasmic reticulum protein 1 |
|---|---|
| UniProt accession | Q9Y6X1 |
| Gene | SERP1 |
| Organism | Homo sapiens |
| Length | 66 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (96)
Diseases linked to this target (Open Targets).
- Marinesco-Sjögren syndrome · score 0.12
- lymphocyte count · score 0.09
- response to vaccine · score 0.09
- congenital hypothyroidism · score 0.07
- neoplasm · score 0.07
- pancreatic neoplasm · score 0.07
- Spinal cord injury · score 0.05
- osteosarcoma · score 0.05
- transient neonatal diabetes mellitus · score 0.04
- MODY · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6X1-F1 | alphafold | PREDICTED | 76.89 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6X1.
Amino-acid sequence (66 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SERP1?
The strongest Open Targets associations for SERP1 are Marinesco-Sjögren syndrome, lymphocyte count, response to vaccine, congenital hypothyroidism and neoplasm.
How long is the SERP1 protein?
The Homo sapiens SERP1 protein (UniProt Q9Y6X1) is 66 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6X1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6X1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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