Soluble lamin-associated protein of 75 kDa (FAM169A)
Homo sapiens — UniProt Q9Y6X4
Data last refreshed: (UniProt release unknown)
Key facts
Soluble lamin-associated protein of 75 kDa (FAM169A) is a protein from Homo sapiens identified by UniProt accession Q9Y6X4, 670 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.
- UniProt accession: Q9Y6X4; gene symbol FAM169A.
- Organism: Homo sapiens.
- Length: 670 amino acids.
- Top disease associations (Open Targets): protein measurement, C-reactive protein measurement and low density lipoprotein cholesterol measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Soluble lamin-associated protein of 75 kDa |
|---|---|
| UniProt accession | Q9Y6X4 |
| Gene | FAM169A |
| Organism | Homo sapiens |
| Length | 670 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (30)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.33
- C-reactive protein measurement · score 0.20
- low density lipoprotein cholesterol measurement · score 0.16
- total cholesterol measurement · score 0.14
- heel bone mineral density · score 0.05
- colorectal adenocarcinoma · score 0.04
- neurofibrillary tangles measurement · score 0.04
- lung carcinoma · score 0.03
- clear cell renal carcinoma · score 0.03
- lumbar disc degeneration · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6X4-F1 | alphafold | PREDICTED | 60.88 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6X4.
Amino-acid sequence (670 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAM169A?
The strongest Open Targets associations for FAM169A are protein measurement, C-reactive protein measurement, low density lipoprotein cholesterol measurement, total cholesterol measurement and heel bone mineral density.
How long is the FAM169A protein?
The Homo sapiens FAM169A protein (UniProt Q9Y6X4) is 670 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6X4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6X4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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