Unconventional myosin-XVI (MYO16)
Homo sapiens — UniProt Q9Y6X6
Data last refreshed: (UniProt release unknown)
Key facts
Unconventional myosin-XVI (MYO16) is a protein from Homo sapiens identified by UniProt accession Q9Y6X6, 1858 residues long. MolForge cross-references it against 0 known binders and 85 disease associations.
- UniProt accession: Q9Y6X6; gene symbol MYO16.
- Organism: Homo sapiens.
- Length: 1858 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, erythrocyte count and mean corpuscular hemoglobin.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Unconventional myosin-XVI |
|---|---|
| UniProt accession | Q9Y6X6 |
| Gene | MYO16 |
| Organism | Homo sapiens |
| Length | 1858 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (85)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.51
- erythrocyte count · score 0.49
- mean corpuscular hemoglobin · score 0.47
- mean corpuscular hemoglobin concentration · score 0.45
- eosinophil count · score 0.45
- brain measurement · score 0.41
- mean reticulocyte volume · score 0.41
- monocyte count · score 0.41
- red blood cell density measurement · score 0.40
- chronotype measurement · score 0.39
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6X6-F1 | alphafold | PREDICTED | 62.27 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6X6.
Amino-acid sequence (1858 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MYO16?
The strongest Open Targets associations for MYO16 are mean corpuscular volume, erythrocyte count, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration and eosinophil count.
How long is the MYO16 protein?
The Homo sapiens MYO16 protein (UniProt Q9Y6X6) is 1858 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6X6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6X6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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