Zinc fingers and homeoboxes protein 2 (ZHX2)
Homo sapiens — UniProt Q9Y6X8
Data last refreshed: (UniProt release unknown)
Key facts
Zinc fingers and homeoboxes protein 2 (ZHX2) is a protein from Homo sapiens identified by UniProt accession Q9Y6X8, 837 residues long. MolForge cross-references it against 0 known binders and 105 disease associations.
- UniProt accession: Q9Y6X8; gene symbol ZHX2.
- Organism: Homo sapiens.
- Length: 837 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, mean reticulocyte volume and mean corpuscular volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc fingers and homeoboxes protein 2 |
|---|---|
| UniProt accession | Q9Y6X8 |
| Gene | ZHX2 |
| Organism | Homo sapiens |
| Length | 837 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (105)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.51
- mean reticulocyte volume · score 0.41
- mean corpuscular volume · score 0.41
- body height · score 0.36
- forced expiratory volume · score 0.32
- appendicular lean mass · score 0.30
- lymphocyte count · score 0.29
- sitting height measurement · score 0.25
- fat body mass · score 0.24
- lean body mass · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6X8-F1 | alphafold | PREDICTED | 59.01 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6X8.
Amino-acid sequence (837 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZHX2?
The strongest Open Targets associations for ZHX2 are neurodegenerative disease, mean reticulocyte volume, mean corpuscular volume, body height and forced expiratory volume.
How long is the ZHX2 protein?
The Homo sapiens ZHX2 protein (UniProt Q9Y6X8) is 837 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6X8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6X8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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