Influenza virus NS1A-binding protein (IVNS1ABP)
Homo sapiens — UniProt Q9Y6Y0
Data last refreshed: (UniProt release unknown)
Key facts
Influenza virus NS1A-binding protein (IVNS1ABP) is a protein from Homo sapiens identified by UniProt accession Q9Y6Y0, 642 residues long. MolForge cross-references it against 0 known binders and 53 disease associations.
- UniProt accession: Q9Y6Y0; gene symbol IVNS1ABP.
- Organism: Homo sapiens.
- Length: 642 amino acids.
- Top disease associations (Open Targets): immunodeficiency 70, monocyte count and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Influenza virus NS1A-binding protein |
|---|---|
| UniProt accession | Q9Y6Y0 |
| Gene | IVNS1ABP |
| Organism | Homo sapiens |
| Length | 642 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (53)
Diseases linked to this target (Open Targets).
- immunodeficiency 70 · score 0.55
- monocyte count · score 0.42
- neurodegenerative disease · score 0.42
- monocyte percentage of leukocytes · score 0.38
- platelet count · score 0.36
- lymphocyte percentage of leukocytes · score 0.35
- lymphocyte:monocyte ratio · score 0.28
- reticulocyte count · score 0.27
- reticulocyte measurement · score 0.27
- granulocyte percentage of myeloid white cells · score 0.26
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y6Y0-F1 | alphafold | PREDICTED | 84.72 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y6Y0.
Amino-acid sequence (642 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IVNS1ABP?
The strongest Open Targets associations for IVNS1ABP are immunodeficiency 70, monocyte count, neurodegenerative disease, monocyte percentage of leukocytes and platelet count.
How long is the IVNS1ABP protein?
The Homo sapiens IVNS1ABP protein (UniProt Q9Y6Y0) is 642 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y6Y0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y6Y0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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