Synaptotagmin-15B (SYT15B)
Homo sapiens — UniProt X6R8R1
Data last refreshed: (UniProt release unknown)
Key facts
Synaptotagmin-15B (SYT15B) is a protein from Homo sapiens identified by UniProt accession X6R8R1, 474 residues long. MolForge cross-references it against 0 known binders and 3 disease associations.
- UniProt accession: X6R8R1; gene symbol SYT15B.
- Organism: Homo sapiens.
- Length: 474 amino acids.
- Top disease associations (Open Targets): myxosarcoma, esophageal squamous cell carcinoma and idiopathic pulmonary fibrosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Synaptotagmin-15B |
|---|---|
| UniProt accession | X6R8R1 |
| Gene | SYT15B |
| Organism | Homo sapiens |
| Length | 474 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (3)
Diseases linked to this target (Open Targets).
- myxosarcoma · score 0.02
- esophageal squamous cell carcinoma · score 0.01
- idiopathic pulmonary fibrosis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-X6R8R1-F1 | alphafold | PREDICTED | 71.51 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for X6R8R1.
Amino-acid sequence (474 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SYT15B?
The strongest Open Targets associations for SYT15B are myxosarcoma, esophageal squamous cell carcinoma and idiopathic pulmonary fibrosis.
How long is the SYT15B protein?
The Homo sapiens SYT15B protein (UniProt X6R8R1) is 474 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB X6R8R1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB X6R8R1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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