Acetyldigitoxin

CARDIOVASCULAR SYSTEM

Key facts

Acetyldigitoxin is an ofm drug catalogued in DrugCentral. It was first approved by the FDA in 1975. DrugCentral lists 1 molecular target, including ATP1A1|ATP1B1|ATP1A3|ATP1B2|ATP1A2|ATP1B3|FXYD2|ATP1A4. Recorded indications include Atrial fibrillation and Congestive heart failure.

• Approval status: ofm (first approved 1975 by the FDA).
• Molecular targets: ATP1A1|ATP1B1|ATP1A3|ATP1B2|ATP1A2|ATP1B3|FXYD2|ATP1A4 (1 listed in DrugCentral).
• Indications: Atrial fibrillation and Congestive heart failure.
• ATC code: C01AA01 (Digitalis glycosides).
• Molecular formula: C43H66O14; molecular weight 806.99 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (2)

• Atrial fibrillation
• Congestive heart failure

Mechanism & targets

Molecular targets (1)

Target	Gene	Action	Activity
Sodium/potassium-transporting ATPase	ATP1A1|ATP1B1|ATP1A3|ATP1B2|ATP1A2|ATP1B3|FXYD2|ATP1A4	inhibitor	—

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1975-04-24	FDA	—	NOVARTIS

ATC classification

ATC code	Therapeutic hierarchy
C01AA01	CARDIOVASCULAR SYSTEM › CARDIAC THERAPY › CARDIAC GLYCOSIDES › Digitalis glycosides

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Acetyldigitoxin is on its molecule page.

• Molecular formula: C₄₃H₆₆O₁₄
• Molecular weight: 806.99 g/mol
• CAS number: 1111-39-3
• InChIKey: HPMZBILYSWLILX-UMDUKNJSSA-N
• PubChem CID: 5284512

C[C@H]1O[C@H](C[C@H](OC(C)=O)[C@@H]1O)O[C@H]1[C@@H](O)C[C@H](O[C@H]2[C@@H](O)C[C@H](O[C@H]3CC[C@@]4(C)[C@H](CC[C@@H]5[C@@H]4CC[C@]4(C)[C@H](CC[C@]54O)C4=CC(=O)OC4)C3)O[C@@H]2C)O[C@@H]1C

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Acetyldigitoxin used for?

DrugCentral lists the following indications for Acetyldigitoxin: Atrial fibrillation and Congestive heart failure.

How does Acetyldigitoxin work?

Its molecular targets in DrugCentral include ATP1A1|ATP1B1|ATP1A3|ATP1B2|ATP1A2|ATP1B3|FXYD2|ATP1A4 (inhibitor).

When was Acetyldigitoxin first approved?

Acetyldigitoxin was first approved by the FDA in 1975.

What is the chemical formula of Acetyldigitoxin?

Acetyldigitoxin has the molecular formula C43H66O14 and a molecular weight of 806.99 g/mol.

Sources

• DrugCentral drug card 67 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL3545057 — compound record and bioactivity
• PubChem CID 5284512 — chemical identifiers
• DrugBank DB00511 — drug record
• FDA UNII 0ZV4Q4L2FU — substance identity
• DailyMed: FDA labels for Acetyldigitoxin — current prescribing information (label search)

How this page is built: methodology · editorial policy & corrections.