Acetylmethadol

Drug profile

Key facts

Acetylmethadol is a drug catalogued in DrugCentral. DrugCentral lists 2 molecular targets, including KCNH2 and OPRM1. Recorded indications include Opioid dependence.

• Molecular targets: KCNH2 and OPRM1 (2 listed in DrugCentral).
• Indications: Opioid dependence.
• Molecular formula: C23H31NO2; molecular weight 353.51 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Opioid dependence

Contraindications (23)

• Acute exacerbation of asthma
• Alcoholism
• Benign intracranial hypertension
• Benign prostatic hyperplasia
• Cholecystitis
• Chronic disease of respiratory system
• Conduction disorder of the heart
• Decreased respiratory function
• Disease of liver
• Disorder of gallbladder
• Disorder of gastrointestinal tract
• Drug AND/OR toxin-induced diarrhea
• General anesthesia
• Hypothyroidism
• Injury of head
• Kidney disease
• Lesion of brain
• Mood swings
• Operation on gastrointestinal tract
• Procedure on urinary system
• Pseudomembranous enterocolitis
• Suicidal thoughts
• Urethral stricture

Mechanism & targets

Molecular targets (2)

Target	Gene	Action	Activity
Potassium voltage-gated channel subfamily H member 2	KCNH2	unknown	IC50 5.66
Mu-type opioid receptor	OPRM1	agonist	—

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Acetylmethadol is on its molecule page.

• Molecular formula: C₂₃H₃₁NO₂
• Molecular weight: 353.51 g/mol
• CAS number: 509-74-0
• InChIKey: XBMIVRRWGCYBTQ-UHFFFAOYSA-N
• PubChem CID: 10517

CCC(OC(C)=O)C(CC(C)N(C)C)(C1=CC=CC=C1)C1=CC=CC=C1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Acetylmethadol used for?

DrugCentral lists the following indications for Acetylmethadol: Opioid dependence.

How does Acetylmethadol work?

Its molecular targets in DrugCentral include KCNH2 and OPRM1 (agonist).

What is the chemical formula of Acetylmethadol?

Acetylmethadol has the molecular formula C23H31NO2 and a molecular weight of 353.51 g/mol.

Sources

• DrugCentral drug card 1729 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL170179 — compound record and bioactivity
• PubChem CID 10517 — chemical identifiers
• DrugBank DB01433 — drug record
• FDA UNII L59OC40KWJ — substance identity
• UniProt Q12809 (KCNH2) — target protein
• UniProt P35372 (OPRM1) — target protein

How this page is built: methodology · editorial policy & corrections.