Butylphthalide

Drug profile

Key facts

Butylphthalide is a drug catalogued in DrugCentral. It was first approved by the China Food and Drug Administration (CFDA) in 2002. DrugCentral lists 1 molecular target, including KCNK2. Recorded indications include Ischemic stroke.

• Molecular targets: KCNK2 (1 listed in DrugCentral).
• Indications: Ischemic stroke.
• Molecular formula: C12H14O2; molecular weight 190.24 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Ischemic stroke

Mechanism & targets

Molecular targets (1)

Target	Gene	Action	Activity
Potassium channel subfamily K member 2	KCNK2	blocker	IC50 7.22

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
2002-09-30	China Food and Drug Administration (CFDA)	—	CSPC Ouyi Pharmaceutical

Chemical structure

• Molecular formula: C₁₂H₁₄O₂
• Molecular weight: 190.24 g/mol
• CAS number: 6066-49-5
• InChIKey: HJXMNVQARNZTEE-UHFFFAOYSA-N
• PubChem CID: 61361

CCCCC1OC(=O)C2=C1C=CC=C2

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Butylphthalide used for?

DrugCentral lists the following indications for Butylphthalide: Ischemic stroke.

How does Butylphthalide work?

Its molecular targets in DrugCentral include KCNK2 (blocker).

When was Butylphthalide first approved?

Butylphthalide was first approved by the China Food and Drug Administration (CFDA) in 2002.

What is the chemical formula of Butylphthalide?

Butylphthalide has the molecular formula C12H14O2 and a molecular weight of 190.24 g/mol.

Sources

• DrugCentral drug card 5257 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• PubChem CID 61361 — chemical identifiers
• DrugBank DB12749 — drug record
• FDA UNII 822Q956KGM — substance identity
• UniProt O95069 (KCNK2) — target protein

How this page is built: methodology · editorial policy & corrections.