Cinoxacin

ANTIINFECTIVES FOR SYSTEMIC USE

Key facts

Cinoxacin is an ofm drug catalogued in DrugCentral. It was first approved by the FDA in 1980. DrugCentral lists 2 molecular targets, including CA2 and gyrA|gyrB. Recorded indications include Urinary tract infectious disease.

• Approval status: ofm (first approved 1980 by the FDA).
• Molecular targets: CA2 and gyrA|gyrB (2 listed in DrugCentral).
• Indications: Urinary tract infectious disease.
• ATC code: J01MB06 (Other quinolones).
• Molecular formula: C12H10N2O5; molecular weight 262.22 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Urinary tract infectious disease

Mechanism & targets

Molecular targets (2)

Target	Gene	Action	Activity
Carbonic anhydrase 2	CA2	unknown	IC50 4.08
DNA gyrase	gyrA|gyrB	inhibitor	—

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1980-06-13	FDA	—	LILLY

ATC classification

ATC code	Therapeutic hierarchy
J01MB06	ANTIINFECTIVES FOR SYSTEMIC USE › ANTIBACTERIALS FOR SYSTEMIC USE › QUINOLONE ANTIBACTERIALS › Other quinolones

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Cinoxacin is on its molecule page.

• Molecular formula: C₁₂H₁₀N₂O₅
• Molecular weight: 262.22 g/mol
• CAS number: 28657-80-9
• InChIKey: VDUWPHTZYNWKRN-UHFFFAOYSA-N
• PubChem CID: 2762

CCN1N=C(C(O)=O)C(=O)C2=C1C=C1OCOC1=C2

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Cinoxacin used for?

DrugCentral lists the following indications for Cinoxacin: Urinary tract infectious disease.

How does Cinoxacin work?

Its molecular targets in DrugCentral include CA2 and gyrA|gyrB (inhibitor).

When was Cinoxacin first approved?

Cinoxacin was first approved by the FDA in 1980.

What is the chemical formula of Cinoxacin?

Cinoxacin has the molecular formula C12H10N2O5 and a molecular weight of 262.22 g/mol.

Sources

• DrugCentral drug card 657 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1208 — compound record and bioactivity
• PubChem CID 2762 — chemical identifiers
• DrugBank DB00827 — drug record
• FDA UNII LMK22VUH23 — substance identity
• DailyMed: FDA labels for Cinoxacin — current prescribing information (label search)
• UniProt P00918 (CA2) — target protein

How this page is built: methodology · editorial policy & corrections.