Corbadrine
Drug profile
Also known as: (-)-alpha-(1-Aminoethyl)-3,4-dihydroxybenzyl alcohol, levoepinefrina, levonordefrin
Data last refreshed: (DrugCentral release 2024-11-01)
Key facts
Corbadrine is an ofm drug catalogued in DrugCentral. It was first approved by the FDA in 1960. DrugCentral lists 4 molecular targets, including Adra2b|Adra2c|Adra2a, ADRA1D and Adra1b|Adra1d|Adra1a.
- Approval status: ofm (first approved 1960 by the FDA).
- Molecular targets: Adra2b|Adra2c|Adra2a, ADRA1D, Adra1b|Adra1d|Adra1a and ADRA2A|ADRA2B|ADRA2C (4 listed in DrugCentral).
- Molecular formula: C9H13NO3; molecular weight 183.21 g/mol.
Mechanism & targets
Molecular targets (4)
| Target | Gene | Action | Activity |
|---|---|---|---|
| Adrenergic receptor alpha-2 | Adra2b|Adra2c|Adra2a | unknown | Ki 6.69 |
| Alpha-1D adrenergic receptor | ADRA1D | agonist | Ki 5.60 |
| Adrenergic receptor alpha-1 | Adra1b|Adra1d|Adra1a | unknown | Ki 5.44 |
| Adrenergic receptor alpha-2 | ADRA2A|ADRA2B|ADRA2C | agonist | — |
Regulatory approvals (1)
| Date | Agency | Marketed as | Applicant | Orphan |
|---|---|---|---|---|
| 1960-01-06 | FDA | — | EASTMAN KODAK |
Chemical structure
| Molecular formula | C9H13NO3 |
|---|---|
| Molecular weight | 183.21 g/mol |
| CAS number | — |
| InChIKey | GEFQWZLICWMTKF-CDUCUWFYSA-N |
| PubChem CID | 164739 |
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
How does Corbadrine work?
Its molecular targets in DrugCentral include Adra2b|Adra2c|Adra2a, ADRA1D (agonist), Adra1b|Adra1d|Adra1a and ADRA2A|ADRA2B|ADRA2C (agonist).
When was Corbadrine first approved?
Corbadrine was first approved by the FDA in 1960.
What is the chemical formula of Corbadrine?
Corbadrine has the molecular formula C9H13NO3 and a molecular weight of 183.21 g/mol.
Browse: all drugs starting with C · drug guides by category · protein targets A–Z.
Sources
- DrugCentral drug card 4482 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
- ChEMBL CHEMBL677 — compound record and bioactivity
- PubChem CID 164739 — chemical identifiers
- DrugBank DB06707 — drug record
- FDA UNII V008L6478D — substance identity
- DailyMed: FDA labels for Corbadrine — current prescribing information (label search)
- UniProt P25100 (ADRA1D) — target protein
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