Cysteine

Drug profile

Key facts

Cysteine is an ofp drug catalogued in DrugCentral. It was first approved by the FDA in 1986. DrugCentral lists 1 molecular target, including SLC7A11. Recorded indications include Amyloidosis, Atelectasis due to Mucous Obstruction, Bronchiectasis and Bronchitis.

• Approval status: ofp (first approved 1986 by the FDA).
• Molecular targets: SLC7A11 (1 listed in DrugCentral).
• Indications: Amyloidosis, Atelectasis due to Mucous Obstruction, Bronchiectasis, Bronchitis and Contrast Media-Induced Nephrotoxicity Prevention and others.
• Molecular formula: C3H7NO2S; molecular weight 121.16 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (9)

• Amyloidosis
• Atelectasis due to Mucous Obstruction
• Bronchiectasis
• Bronchitis
• Contrast Media-Induced Nephrotoxicity Prevention
• Cystic fibrosis of the lung
• General anesthesia
• Poisoning by acetaminophen
• Thick Bronchial Secretions

Off-label uses (2)

• Bronchial Studies
• Meconium ileus

Contraindications (9)

• Acute exacerbation of asthma
• Bronchospasm
• Classical phenylketonuria
• Decreased respiratory function
• Esophageal varices
• Gastrointestinal hemorrhage
• Gastrointestinal ulcer
• Low blood pressure
• Peptic ulcer

Mechanism & targets

Molecular targets (1)

Target	Gene	Action	Activity
Cystine/glutamate transporter	SLC7A11	unknown	Ki 4.23

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1986-10-22	FDA	—	HOSPIRA

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Parenteral nutrition associated liver disease	296.4

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Cysteine is on its molecule page.

• Molecular formula: C₃H₇NO₂S
• Molecular weight: 121.16 g/mol
• CAS number: —
• InChIKey: XUJNEKJLAYXESH-REOHCLBHSA-N
• PubChem CID: 5862

N[C@@H](CS)C(O)=O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Cysteine used for?

DrugCentral lists the following indications for Cysteine: Amyloidosis, Atelectasis due to Mucous Obstruction, Bronchiectasis, Bronchitis, Contrast Media-Induced Nephrotoxicity Prevention, Cystic fibrosis of the lung, General anesthesia and Poisoning by acetaminophen and others.

How does Cysteine work?

Its molecular targets in DrugCentral include SLC7A11.

When was Cysteine first approved?

Cysteine was first approved by the FDA in 1986.

What is the chemical formula of Cysteine?

Cysteine has the molecular formula C3H7NO2S and a molecular weight of 121.16 g/mol.

Sources

• DrugCentral drug card 769 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1200630 — compound record and bioactivity
• PubChem CID 5862 — chemical identifiers
• DrugBank DB00151 — drug record
• FDA UNII K848JZ4886 — substance identity
• DailyMed: FDA labels for Cysteine — current prescribing information (label search)
• UniProt Q9UPY5 (SLC7A11) — target protein
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

How this page is built: methodology · editorial policy & corrections.