Delamanid

ANTIINFECTIVES FOR SYSTEMIC USE

Key facts

Delamanid is a drug catalogued in DrugCentral. It was first approved by the EMA in 2013. Recorded indications include Drug resistant tuberculosis.

• Indications: Drug resistant tuberculosis.
• ATC code: J04AK06 (Other drugs for treatment of tuberculosis).
• Molecular formula: C25H25F3N4O6; molecular weight 534.49 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Drug resistant tuberculosis

Regulatory approvals (2)

Date	Agency	Marketed as	Applicant	Orphan
2014-07-04	PMDA	—	—
2013-11-22	EMA	—	—

ATC classification

ATC code	Therapeutic hierarchy
J04AK06	ANTIINFECTIVES FOR SYSTEMIC USE › ANTIMYCOBACTERIALS › DRUGS FOR TREATMENT OF TUBERCULOSIS › Other drugs for treatment of tuberculosis

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Electrocardiogram QT prolonged	680.3
Neuropathy peripheral	276.4
Anaemia	213.3
Incorrect product administration duration	128.4
Vomiting	128.2
Off label use	115.3
Tuberculosis	107.5
Intentional product use issue	88.8
Hypokalaemia	86.4
Optic neuritis	79.5
Psychotic disorder	71.3
Drug resistance	70.2

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Delamanid is on its molecule page.

• Molecular formula: C₂₅H₂₅F₃N₄O₆
• Molecular weight: 534.49 g/mol
• CAS number: 681492-22-8
• InChIKey: XDAOLTSRNUSPPH-XMMPIXPASA-N
• PubChem CID: 6480466

C[C@]1(COC2=CC=C(C=C2)N2CCC(CC2)OC2=CC=C(OC(F)(F)F)C=C2)CN2C=C(N=C2O1)[N+]([O-])=O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Delamanid used for?

DrugCentral lists the following indications for Delamanid: Drug resistant tuberculosis.

When was Delamanid first approved?

Delamanid was first approved by the EMA in 2013.

What is the chemical formula of Delamanid?

Delamanid has the molecular formula C25H25F3N4O6 and a molecular weight of 534.49 g/mol.

Sources

• DrugCentral drug card 4819 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL218650 — compound record and bioactivity
• PubChem CID 6480466 — chemical identifiers
• DrugBank DB11637 — drug record
• FDA UNII 8OOT6M1PC7 — substance identity
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

How this page is built: methodology · editorial policy & corrections.