Evans blue

Drug profile

Key facts

Evans blue is an ofm drug catalogued in DrugCentral. DrugCentral lists 6 molecular targets, including Slc17a8, REP and ENPP2.

• Approval status: ofm.
• Molecular targets: Slc17a8, REP, ENPP2 and PTP1 (6 listed in DrugCentral).
• Molecular formula: C34H28N6O14S4; molecular weight 872.87 g/mol.

Mechanism & targets

Molecular targets (6)

Target	Gene	Action	Activity
Vesicular glutamate transporter 3	Slc17a8	unknown	Ki 7.40
Replicase polyprotein 1ab	REP	unknown	IC50 6.70
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	ENPP2	unknown	Ki 6.08
Tyrosine-protein phosphatase 1	PTP1	unknown	IC50 5.92
Tyrosine-protein phosphatase non-receptor type 1	PTPN1	unknown	IC50 5.89
Luciferin 4-monooxygenase	—	unknown	IC50 5.77

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
—	FDA	—	PARKE DAVIS

Chemical structure

• Molecular formula: C₃₄H₂₈N₆O₁₄S₄
• Molecular weight: 872.87 g/mol
• CAS number: 314-13-6
• InChIKey: COXVTLYNGOIATD-HVMBLDELSA-N
• PubChem CID: 9409

CC1=C(C=CC(=C1)C1=CC(C)=C(C=C1)\N=N\C1=C(O)C2=C(N)C(=CC(=C2C=C1)S(O)(=O)=O)S(O)(=O)=O)\N=N\C1=CC=C2C(=CC(=C(N)C2=C1O)S(O)(=O)=O)S(O)(=O)=O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Evans blue work?

Its molecular targets in DrugCentral include Slc17a8, REP, ENPP2 and PTP1.

What is the chemical formula of Evans blue?

Evans blue has the molecular formula C34H28N6O14S4 and a molecular weight of 872.87 g/mol.

Sources

• DrugCentral drug card 3217 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1200712 — compound record and bioactivity
• PubChem CID 9409 — chemical identifiers
• DrugBank DB09361 — drug record
• FDA UNII 45PG892GO1 — substance identity
• DailyMed: FDA labels for Evans blue — current prescribing information (label search)
• UniProt Q13822 (ENPP2) — target protein
• UniProt P18031 (PTPN1) — target protein

How this page is built: methodology · editorial policy & corrections.