Glafenine

NERVOUS SYSTEM

Key facts

Glafenine is a drug catalogued in DrugCentral. DrugCentral lists 2 molecular targets, including ABCB11 and Abcb11.

• Molecular targets: ABCB11 and Abcb11 (2 listed in DrugCentral).
• ATC code: N02BG03 (Other analgesics and antipyretics).
• Molecular formula: C19H17ClN2O4; molecular weight 372.81 g/mol.

Mechanism & targets

Molecular targets (2)

Target	Gene	Action	Activity
Bile salt export pump	ABCB11	unknown	IC50 4.65
Bile salt export pump	Abcb11	unknown	IC50 4.49

ATC classification

ATC code	Therapeutic hierarchy
N02BG03	NERVOUS SYSTEM › ANALGESICS › OTHER ANALGESICS AND ANTIPYRETICS › Other analgesics and antipyretics

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Glafenine is on its molecule page.

• Molecular formula: C₁₉H₁₇ClN₂O₄
• Molecular weight: 372.81 g/mol
• CAS number: 3820-67-5
• InChIKey: GWOFUCIGLDBNKM-UHFFFAOYSA-N
• PubChem CID: 3474

OCC(O)COC(=O)C1=C(NC2=CC=NC3=CC(Cl)=CC=C23)C=CC=C1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Glafenine work?

Its molecular targets in DrugCentral include ABCB11 and Abcb11.

What is the chemical formula of Glafenine?

Glafenine has the molecular formula C19H17ClN2O4 and a molecular weight of 372.81 g/mol.

Sources

• DrugCentral drug card 1297 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL146095 — compound record and bioactivity
• PubChem CID 3474 — chemical identifiers
• DrugBank DB08963 — drug record
• FDA UNII 46HL4I09AH — substance identity
• UniProt O95342 (ABCB11) — target protein

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