Gluconolactone

Calculi Dissolution Agent

Key facts

Gluconolactone is an ofp drug in the Calculi Dissolution Agent class catalogued in DrugCentral. It was first approved by the FDA in 1990. Its mechanism of action is classified as Irrigation. DrugCentral lists 1 molecular target, including GBA. Recorded indications include Urinary bladder stone.

• Approval status: ofp (first approved 1990 by the FDA).
• Drug class: Calculi Dissolution Agent.
• Mechanism of action: Irrigation.
• Molecular targets: GBA (1 listed in DrugCentral).
• Indications: Urinary bladder stone.
• Molecular formula: C6H10O6; molecular weight 178.14 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Urinary bladder stone

Mechanism & targets

• Mechanism of action (MoA): Irrigation
• Established pharmacologic class: Calculi Dissolution Agent

Molecular targets (1)

Target	Gene	Action	Activity
Glucosylceramidase	GBA	unknown	Ki 4.52

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1990-10-02	FDA	—	UNITED GUARDIAN	Yes

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Gluconolactone is on its molecule page.

• Molecular formula: C₆H₁₀O₆
• Molecular weight: 178.14 g/mol
• CAS number: 90-80-2
• InChIKey: PHOQVHQSTUBQQK-SQOUGZDYSA-N
• PubChem CID: 7027

OC[C@H]1OC(=O)[C@H](O)[C@@H](O)[C@@H]1O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Gluconolactone used for?

DrugCentral lists the following indications for Gluconolactone: Urinary bladder stone.

How does Gluconolactone work?

Gluconolactone is classified as Irrigation; its molecular targets in DrugCentral include GBA.

When was Gluconolactone first approved?

Gluconolactone was first approved by the FDA in 1990.

What drug class does Gluconolactone belong to?

Gluconolactone is in the Calculi Dissolution Agent class.

What is the chemical formula of Gluconolactone?

Gluconolactone has the molecular formula C6H10O6 and a molecular weight of 178.14 g/mol.

Sources

• DrugCentral drug card 5144 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1200829 — compound record and bioactivity
• PubChem CID 7027 — chemical identifiers
• DrugBank DB04564 — drug record
• FDA UNII WQ29KQ9POT — substance identity
• DailyMed: FDA labels for Gluconolactone — current prescribing information (label search)
• UniProt P04062 (GBA) — target protein

How this page is built: methodology · editorial policy & corrections.