Ilaprazole

ALIMENTARY TRACT AND METABOLISM

Key facts

Ilaprazole is a drug catalogued in DrugCentral. It was first approved by the Korean Food and Drug Administration (KFDA) in 2008. DrugCentral lists 1 molecular target, including ATP4A|ATP4B. Recorded indications include Gastroesophageal reflux disease and Peptic ulcer.

• Molecular targets: ATP4A|ATP4B (1 listed in DrugCentral).
• Indications: Gastroesophageal reflux disease and Peptic ulcer.
• ATC code: A02BC11 (Proton pump inhibitors).
• Molecular formula: C19H18N4O2S; molecular weight 366.44 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (2)

• Gastroesophageal reflux disease
• Peptic ulcer

Mechanism & targets

Molecular targets (1)

Target	Gene	Action	Activity
Potassium-transporting ATPase	ATP4A|ATP4B	inhibitor	—

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
2008-10-28	Korean Food and Drug Administration (KFDA)	—	—

ATC classification

ATC code	Therapeutic hierarchy
A02BC11	ALIMENTARY TRACT AND METABOLISM › DRUGS FOR ACID RELATED DISORDERS › DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD) › Proton pump inhibitors

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Occupational dermatitis	83.5
Occupational exposure to air contaminants	73.2

Chemical structure

• Molecular formula: C₁₉H₁₈N₄O₂S
• Molecular weight: 366.44 g/mol
• CAS number: 172152-36-2
• InChIKey: HRRXCXABAPSOCP-UHFFFAOYSA-N
• PubChem CID: 214351

COC1=CC=NC(CS(=O)C2=NC3=C(N2)C=CC(=C3)N2C=CC=C2)=C1C

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Ilaprazole used for?

DrugCentral lists the following indications for Ilaprazole: Gastroesophageal reflux disease and Peptic ulcer.

How does Ilaprazole work?

Its molecular targets in DrugCentral include ATP4A|ATP4B (inhibitor).

When was Ilaprazole first approved?

Ilaprazole was first approved by the Korean Food and Drug Administration (KFDA) in 2008.

What is the chemical formula of Ilaprazole?

Ilaprazole has the molecular formula C19H18N4O2S and a molecular weight of 366.44 g/mol.

Sources

• DrugCentral drug card 3961 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL2106370 — compound record and bioactivity
• PubChem CID 214351 — chemical identifiers
• DrugBank DB11964 — drug record
• FDA UNII 776Q6XX45J — substance identity
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

How this page is built: methodology · editorial policy & corrections.