Imidacloprid

Drug profile

Key facts

Imidacloprid is a drug catalogued in DrugCentral. DrugCentral lists 9 molecular targets, including nAChRbeta2, nAChRalpha5 and Soluble acetylcholine receptor.

• Molecular targets: nAChRbeta2, nAChRalpha5, Soluble acetylcholine receptor and Chrna4 (9 listed in DrugCentral).
• Molecular formula: C9H10ClN5O2; molecular weight 255.66 g/mol.

Mechanism & targets

Molecular targets (9)

Target	Gene	Action	Activity
Acetylcholine receptor subunit beta-like 2	nAChRbeta2	unknown	IC50 8.64
Nicotinic acetylcholine receptor alpha 5 subunit	nAChRalpha5	unknown	IC50 8.59
Soluble acetylcholine receptor	—	unknown	Ki 7.72
Neuronal acetylcholine receptor subunit alpha-4	Chrna4	unknown	Ki 7.30
Acetylcholine-binding protein	—	unknown	Ki 6.01
Neuronal acetylcholine receptor subunit alpha-4	CHRNA4	unknown	Ki 6.01
Nicotinic acetylcholine receptor alpha8 subunit	—	unknown	EC50 5.88
Neuronal acetylcholine receptor subunit alpha-4	Chrna4	unknown	IC50 5.58
Neuronal acetylcholine receptor subunit alpha-3	CHRNA3	unknown	IC50 4.85

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
—	FDA	—	—

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Imidacloprid is on its molecule page.

• Molecular formula: C₉H₁₀ClN₅O₂
• Molecular weight: 255.66 g/mol
• CAS number: 138261-41-3
• InChIKey: YWTYJOPNNQFBPC-UHFFFAOYSA-N
• PubChem CID: 86287518

[O-][N+](=O)NC1=NCCN1CC2=CC=C(Cl)N=C2

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Imidacloprid work?

Its molecular targets in DrugCentral include nAChRbeta2, nAChRalpha5, Soluble acetylcholine receptor and Chrna4.

What is the chemical formula of Imidacloprid?

Imidacloprid has the molecular formula C9H10ClN5O2 and a molecular weight of 255.66 g/mol.

Sources

• DrugCentral drug card 5559 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL406819 — compound record and bioactivity
• PubChem CID 86287518 — chemical identifiers
• DrugBank DB11421 — drug record
• FDA UNII 3BN7M937V8 — substance identity
• DailyMed: FDA labels for Imidacloprid — current prescribing information (label search)
• UniProt P32297 (CHRNA3) — target protein

How this page is built: methodology · editorial policy & corrections.