Intoplicine

Drug profile

Key facts

Intoplicine is a drug catalogued in DrugCentral. DrugCentral lists 3 molecular targets, including TOP1MT, TOP1 and TOP2A.

• Molecular targets: TOP1MT, TOP1 and TOP2A (3 listed in DrugCentral).
• Molecular formula: C21H24N4O; molecular weight 348.45 g/mol.

Mechanism & targets

Molecular targets (3)

Target	Gene	Action	Activity
DNA topoisomerase I, mitochondrial	TOP1MT	unknown	IC50 6.52
DNA topoisomerase 1	TOP1	unknown	IC50 6.52
DNA topoisomerase 2-alpha	TOP2A	unknown	IC50 5.82

Chemical structure

• Molecular formula: C₂₁H₂₄N₄O
• Molecular weight: 348.45 g/mol
• CAS number: 125974-72-3
• InChIKey: QROONAIPJKQFMC-UHFFFAOYSA-N
• PubChem CID: 65954

CN(C)CCCNC1=NC=C(C)C2=C1C1=C3C=CC(O)=CC3=CC=C1N2

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Intoplicine work?

Its molecular targets in DrugCentral include TOP1MT, TOP1 and TOP2A.

What is the chemical formula of Intoplicine?

Intoplicine has the molecular formula C21H24N4O and a molecular weight of 348.45 g/mol.

Sources

• DrugCentral drug card 1446 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1908351 — compound record and bioactivity
• PubChem CID 65954 — chemical identifiers
• DrugBank DB12868 — drug record
• FDA UNII FB2CIN6HMI — substance identity
• UniProt Q969P6 (TOP1MT) — target protein
• UniProt P11387 (TOP1) — target protein
• UniProt P11388 (TOP2A) — target protein

How this page is built: methodology · editorial policy & corrections.