Irofulven
Drug profile
Also known as: (-)-Irofulven, 6-hydroxymethylacylfulvene, MGI-114
Data last refreshed: (DrugCentral release 2024-11-01)
Key facts
Irofulven is a drug catalogued in DrugCentral. DrugCentral lists 1 molecular target, including CHEK2.
- Molecular targets: CHEK2 (1 listed in DrugCentral).
- Molecular formula: C15H18O3; molecular weight 246.31 g/mol.
Mechanism & targets
Molecular targets (1)
| Target | Gene | Action | Activity |
|---|---|---|---|
| Serine/threonine-protein kinase Chk2 | CHEK2 | unknown | — |
Chemical structure
| Molecular formula | C15H18O3 |
|---|---|
| Molecular weight | 246.31 g/mol |
| CAS number | 158440-71-2 |
| InChIKey | NICJCIQSJJKZAH-AWEZNQCLSA-N |
| PubChem CID | 148189 |
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
How does Irofulven work?
Its molecular targets in DrugCentral include CHEK2.
What is the chemical formula of Irofulven?
Irofulven has the molecular formula C15H18O3 and a molecular weight of 246.31 g/mol.
Browse: all drugs starting with I · drug guides by category · protein targets A–Z.
Sources
- DrugCentral drug card 1483 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
- ChEMBL CHEMBL118218 — compound record and bioactivity
- PubChem CID 148189 — chemical identifiers
- DrugBank DB05786 — drug record
- FDA UNII 6B799IH05A — substance identity
- UniProt O96017 (CHEK2) — target protein
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