Kainic acid

Drug profile

Key facts

Kainic acid is a drug catalogued in DrugCentral. DrugCentral lists 21 molecular targets, including GRIK4, Grik2 and Grik3.

• Molecular targets: GRIK4, Grik2, Grik3 and Grik1|Grik2|Grik3|Grik4|Grik5 (21 listed in DrugCentral).
• Molecular formula: C10H15NO4; molecular weight 213.23 g/mol.

Mechanism & targets

Molecular targets (21)

Target	Gene	Action	Activity
Glutamate receptor ionotropic, kainate 4	GRIK4	unknown	Ki 8.64
Glutamate receptor ionotropic, kainate 2	Grik2	unknown	Ki 8.43
Glutamate receptor ionotropic, kainate 3	Grik3	unknown	Ki 8.42
Glutamate receptor ionotropic, kainate	Grik1|Grik2|Grik3|Grik4|Grik5	unknown	IC50 8.37
Glutamate receptor ionotropic, kainate 4	Grik4	unknown	Ki 8.33
Glutamate receptor ionotropic, kainate 5	GRIK5	unknown	Ki 8.10
Glutamate receptor ionotropic, kainate 3	GRIK3	unknown	Ki 8.00
Glutamate receptor ionotropic, kainate 5	Grik5	unknown	Ki 7.82
Glutamate receptor ionotropic, AMPA	Gria1|Gria2|Gria3|Gria4	unknown	Ki 7.53
Glutamate receptor ionotropic, kainate 2	GRIK2	unknown	Ki 7.49
Glutamate receptor ionotropic, kainate 1	Grik1	unknown	Ki 7.15
Adenosine receptor A3	ADORA3	unknown	IC50 7.11
Glutamate receptor ionotropic, kainate 1	GRIK1	unknown	Ki 6.75
Glutamate receptor 1	Gria1	unknown	Ki 6.32
Glutamate receptor 4	GRIA4	unknown	Ki 5.77
Glutamate receptor 3	Gria3	unknown	Ki 5.70
Glutamate receptor 3	GRIA3	unknown	Ki 5.58
Glutamate receptor 4	Gria4	unknown	Ki 5.45
Glutamate receptor 2	Gria2	unknown	Ki 5.43
Glutamate receptor 1	GRIA1	unknown	Ki 5.13

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Kainic acid is on its molecule page.

• Molecular formula: C₁₀H₁₅NO₄
• Molecular weight: 213.23 g/mol
• CAS number: 487-79-6
• InChIKey: VLSMHEGGTFMBBZ-OOZYFLPDSA-N
• PubChem CID: 10255

CC(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Kainic acid work?

Its molecular targets in DrugCentral include GRIK4, Grik2, Grik3 and Grik1|Grik2|Grik3|Grik4|Grik5.

What is the chemical formula of Kainic acid?

Kainic acid has the molecular formula C10H15NO4 and a molecular weight of 213.23 g/mol.

Sources

• DrugCentral drug card 3201 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL275040 — compound record and bioactivity
• PubChem CID 10255 — chemical identifiers
• FDA UNII SIV03811UC — substance identity
• UniProt Q16099 (GRIK4) — target protein
• UniProt Q16478 (GRIK5) — target protein
• UniProt Q13003 (GRIK3) — target protein
• UniProt Q13002 (GRIK2) — target protein
• UniProt P0DMS8 (ADORA3) — target protein
• UniProt P39086 (GRIK1) — target protein

How this page is built: methodology · editorial policy & corrections.