Lafutidine

ALIMENTARY TRACT AND METABOLISM

Key facts

Lafutidine is a drug catalogued in DrugCentral. Recorded indications include Gastro-esophageal reflux disease with esophagitis.

• Indications: Gastro-esophageal reflux disease with esophagitis.
• ATC code: A02BA08 (H2-receptor antagonists).
• Molecular formula: C22H29N3O4S; molecular weight 431.55 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Gastro-esophageal reflux disease with esophagitis

ATC classification

ATC code	Therapeutic hierarchy
A02BA08	ALIMENTARY TRACT AND METABOLISM › DRUGS FOR ACID RELATED DISORDERS › DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD) › H2-receptor antagonists

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Platelet count decreased	107.7
Interstitial lung disease	78.1
Neutrophil count decreased	43.1
White blood cell count decreased	42.2
Febrile neutropenia	30.8
Decreased appetite	30.5
Hepatic function abnormal	28.2
Anaemia	28.0

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Lafutidine is on its molecule page.

• Molecular formula: C₂₂H₂₉N₃O₄S
• Molecular weight: 431.55 g/mol
• CAS number: 206449-93-6
• InChIKey: KMZQAVXSMUKBPD-DJWKRKHSSA-N
• PubChem CID: 5282136

O=C(CS(=O)CC1=CC=CO1)NC\C=C/COC1=NC=CC(CN2CCCCC2)=C1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Lafutidine used for?

DrugCentral lists the following indications for Lafutidine: Gastro-esophageal reflux disease with esophagitis.

What is the chemical formula of Lafutidine?

Lafutidine has the molecular formula C22H29N3O4S and a molecular weight of 431.55 g/mol.

Sources

• DrugCentral drug card 1537 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1742461 — compound record and bioactivity
• PubChem CID 5282136 — chemical identifiers
• DrugBank DB12770 — drug record
• FDA UNII 49S4O7ADLC — substance identity
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

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