Maxacalcitol

Drug profile

Key facts

Maxacalcitol is a drug catalogued in DrugCentral. DrugCentral lists 2 molecular targets, including VDR and Vdr. Recorded indications include Pustular psoriasis.

• Molecular targets: VDR and Vdr (2 listed in DrugCentral).
• Indications: Pustular psoriasis.
• Molecular formula: C26H42O4; molecular weight 418.62 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Pustular psoriasis

Mechanism & targets

Molecular targets (2)

Target	Gene	Action	Activity
Vitamin D3 receptor	VDR	unknown	EC50 9.07
Vitamin D3 receptor	Vdr	agonist	EC50 8.21

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Shunt stenosis	944.3
Shunt occlusion	512.9
Peripheral arterial occlusive disease	161.1
Angina unstable	91.2
Cardiac failure	79.5
Cerebral infarction	59.6
Shunt infection	59.4
Hypocalcaemia	57.5
Aortic valve stenosis	50.6
Shunt aneurysm	49.3

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Maxacalcitol is on its molecule page.

• Molecular formula: C₂₆H₄₂O₄
• Molecular weight: 418.62 g/mol
• CAS number: 103909-75-7
• InChIKey: DTXXSJZBSTYZKE-ZDQKKZTESA-N
• PubChem CID: 6398761

C[C@H](OCCC(C)(C)O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Maxacalcitol used for?

DrugCentral lists the following indications for Maxacalcitol: Pustular psoriasis.

How does Maxacalcitol work?

Its molecular targets in DrugCentral include VDR and Vdr (agonist).

What is the chemical formula of Maxacalcitol?

Maxacalcitol has the molecular formula C26H42O4 and a molecular weight of 418.62 g/mol.

Sources

• DrugCentral drug card 1638 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL333950 — compound record and bioactivity
• PubChem CID 6398761 — chemical identifiers
• DrugBank DB06272 — drug record
• FDA UNII N2UJM5NBF6 — substance identity
• UniProt P11473 (VDR) — target protein
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

How this page is built: methodology · editorial policy & corrections.