Mefuparib

Drug profile

Key facts

Mefuparib is a drug catalogued in DrugCentral. DrugCentral lists 2 molecular targets, including PARP2 and PARP1.

• Molecular targets: PARP2 and PARP1 (2 listed in DrugCentral).
• Molecular formula: C17H15FN2O2; molecular weight 298.32 g/mol.

Mechanism & targets

Molecular targets (2)

Target	Gene	Action	Activity
Poly [ADP-ribose] polymerase 2	PARP2	inhibitor	IC50 8.72
Poly [ADP-ribose] polymerase 1	PARP1	inhibitor	IC50 8.49

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Mefuparib is on its molecule page.

• Molecular formula: C₁₇H₁₅FN₂O₂
• Molecular weight: 298.32 g/mol
• CAS number: —
• InChIKey: ROBJKLPZIPNAMV-UHFFFAOYSA-N
• PubChem CID: 71488522

CNCC1=CC=C(C=C1)C1=CC2=C(O1)C(=CC(F)=C2)C(N)=O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Mefuparib work?

Its molecular targets in DrugCentral include PARP2 (inhibitor) and PARP1 (inhibitor).

What is the chemical formula of Mefuparib?

Mefuparib has the molecular formula C17H15FN2O2 and a molecular weight of 298.32 g/mol.

Sources

• DrugCentral drug card 5378 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• PubChem CID 71488522 — chemical identifiers
• FDA UNII 9NN2OZ1YX4 — substance identity
• UniProt Q9UGN5 (PARP2) — target protein
• UniProt P09874 (PARP1) — target protein

How this page is built: methodology · editorial policy & corrections.