Mifamurtide
ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
Also known as: junovan, L-MTP-PE, mepact, mifamurtide hydrate, mifamurtide sodium, MTP-PE, muramyl tripeptide phosphatidyl ethanolamine
Data last refreshed: (DrugCentral release 2024-11-01)
Key facts
Mifamurtide is a drug catalogued in DrugCentral. It was first approved by the EMA in 2009. DrugCentral lists 1 molecular target, including NOD2. Recorded indications include Osteosarcoma of bone.
- Molecular targets: NOD2 (1 listed in DrugCentral).
- Indications: Osteosarcoma of bone.
- ATC code: L03AX15 (Other immunostimulants).
- Molecular formula: C59H109N6O19P; molecular weight 1237.52 g/mol.
Indications & contraindications
Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).
Indications (1)
- Osteosarcoma of bone
Mechanism & targets
Molecular targets (1)
| Target | Gene | Action | Activity |
|---|---|---|---|
| Nucleotide-binding oligomerization domain-containing protein 2 | NOD2 | activator | — |
Regulatory approvals (1)
| Date | Agency | Marketed as | Applicant | Orphan |
|---|---|---|---|---|
| 2009-03-06 | EMA | — | Takeda France SAS | Yes |
ATC classification
| ATC code | Therapeutic hierarchy |
|---|---|
L03AX15 | ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS › IMMUNOSTIMULANTS › IMMUNOSTIMULANTS › Other immunostimulants |
Chemical structure
| Molecular formula | C59H109N6O19P |
|---|---|
| Molecular weight | 1237.52 g/mol |
| CAS number | 90825-43-7 |
| InChIKey | JMUHBNWAORSSBD-WKYWBUFDSA-N |
| PubChem CID | 123133557 |
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
What is Mifamurtide used for?
DrugCentral lists the following indications for Mifamurtide: Osteosarcoma of bone.
How does Mifamurtide work?
Its molecular targets in DrugCentral include NOD2 (activator).
When was Mifamurtide first approved?
Mifamurtide was first approved by the EMA in 2009.
What is the chemical formula of Mifamurtide?
Mifamurtide has the molecular formula C59H109N6O19P and a molecular weight of 1237.52 g/mol.
Browse: all drugs starting with M · drug guides by category · protein targets A–Z.
Sources
- DrugCentral drug card 2960 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
- ChEMBL CHEMBL2107354 — compound record and bioactivity
- PubChem CID 123133557 — chemical identifiers
- DrugBank DB13615 — drug record
- FDA UNII 1LM890Q4FY — substance identity
- UniProt Q9HC29 (NOD2) — target protein
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