Moxidectin

ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS

Key facts

Moxidectin is an ofp drug catalogued in DrugCentral. It was first approved by the FDA in 2018. DrugCentral lists 1 molecular target, including GluClX. Recorded indications include Infection by Onchocerca volvulus.

• Approval status: ofp (first approved 2018 by the FDA).
• Molecular targets: GluClX (1 listed in DrugCentral).
• Indications: Infection by Onchocerca volvulus.
• ATC code: P02CX03 (Other antinematodals).
• Molecular formula: C37H53NO8; molecular weight 639.83 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Infection by Onchocerca volvulus

Mechanism & targets

Molecular targets (1)

Target	Gene	Action	Activity
Glutamate-gated chloride channel	GluClX	inhibitor	—

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
2018-06-13	FDA	—	MDGH	Yes

ATC classification

ATC code	Therapeutic hierarchy
P02CX03	ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS › ANTHELMINTICS › ANTINEMATODAL AGENTS › Other antinematodals

Chemical structure

• Molecular formula: C₃₇H₅₃NO₈
• Molecular weight: 639.83 g/mol
• CAS number: —
• InChIKey: YZBLFMPOMVTDJY-LSGXYNIPSA-N
• PubChem CID: 9832912

CO\N=C1/C[C@]2(C[C@@H]3C[C@@H](C\C=C(C)\C[C@@H](C)\C=C\C=C4/CO[C@@H]5[C@H](O)C(C)=C[C@@H](C(=O)O3)[C@]45O)O2)O[C@@H]([C@H]1C)C(\C)=C\C(C)C

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Moxidectin used for?

DrugCentral lists the following indications for Moxidectin: Infection by Onchocerca volvulus.

How does Moxidectin work?

Its molecular targets in DrugCentral include GluClX (inhibitor).

When was Moxidectin first approved?

Moxidectin was first approved by the FDA in 2018.

What is the chemical formula of Moxidectin?

Moxidectin has the molecular formula C37H53NO8 and a molecular weight of 639.83 g/mol.

Sources

• DrugCentral drug card 5286 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL2104415 — compound record and bioactivity
• PubChem CID 9832912 — chemical identifiers
• DrugBank DB11431 — drug record
• FDA UNII NGU5H31YO9 — substance identity
• DailyMed: FDA labels for Moxidectin — current prescribing information (label search)

How this page is built: methodology · editorial policy & corrections.