Pyrvinium

ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS

Key facts

Pyrvinium is an ofm drug catalogued in DrugCentral. DrugCentral lists 6 molecular targets, including CSNK1A1, AR and Fumarate reductase.

• Approval status: ofm.
• Molecular targets: CSNK1A1, AR, Fumarate reductase and SYNJ1 (6 listed in DrugCentral).
• ATC code: P02CX01 (Other antinematodals).
• Molecular formula: C26H28N3; molecular weight 382.53 g/mol.

Mechanism & targets

Molecular targets (6)

Target	Gene	Action	Activity
Casein kinase I isoform alpha	CSNK1A1	unknown	Kd 9.00
Androgen receptor	AR	unknown	IC50 6.72
Fumarate reductase	—	unknown	IC50 6.30
Synaptojanin-1	SYNJ1	unknown	IC50 6.00
Synaptojanin-2	SYNJ2	unknown	IC50 5.90
Serine hydroxymethyltransferase, mitochondrial	SHMT2	unknown	IC50 5.59

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
—	FDA	—	PARKE DAVIS

ATC classification

ATC code	Therapeutic hierarchy
P02CX01	ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS › ANTHELMINTICS › ANTINEMATODAL AGENTS › Other antinematodals

Chemical structure

• Molecular formula: C₂₆H₂₈N₃
• Molecular weight: 382.53 g/mol
• CAS number: 3546-41-6
• InChIKey: QMHSXPLYMTVAMK-UHFFFAOYSA-N
• PubChem CID: 5281035

CN(C)C1=CC=C2C(C=CC(\C=C\C3=C(C)N(C(C)=C3)C3=CC=CC=C3)=[N+]2C)=C1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Pyrvinium work?

Its molecular targets in DrugCentral include CSNK1A1, AR, Fumarate reductase and SYNJ1.

What is the chemical formula of Pyrvinium?

Pyrvinium has the molecular formula C26H28N3 and a molecular weight of 382.53 g/mol.

Sources

• DrugCentral drug card 2335 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1201303 — compound record and bioactivity
• PubChem CID 5281035 — chemical identifiers
• DrugBank DB06816 — drug record
• FDA UNII 6B9991FLU3 — substance identity
• DailyMed: FDA labels for Pyrvinium — current prescribing information (label search)
• UniProt P48729 (CSNK1A1) — target protein
• UniProt P10275 (AR) — target protein
• UniProt O43426 (SYNJ1) — target protein
• UniProt O15056 (SYNJ2) — target protein
• UniProt P34897 (SHMT2) — target protein

How this page is built: methodology · editorial policy & corrections.