Pentagastrin

VARIOUS

Key facts

Pentagastrin is an ofm drug catalogued in DrugCentral. It was first approved by the FDA in 1974. DrugCentral lists 4 molecular targets, including Cckbr, Cckbr and CCKBR.

• Approval status: ofm (first approved 1974 by the FDA).
• Molecular targets: Cckbr, Cckbr, CCKBR and Cckar (4 listed in DrugCentral).
• ATC code: V04CG04 (Tests for gastric secretion).
• Molecular formula: C37H49N7O9S; molecular weight 767.90 g/mol.

Mechanism & targets

Molecular targets (4)

Target	Gene	Action	Activity
Gastrin/cholecystokinin type B receptor	Cckbr	unknown	IC50 9.10
Gastrin/cholecystokinin type B receptor	Cckbr	unknown	IC50 8.17
Gastrin/cholecystokinin type B receptor	CCKBR	unknown	Ki 7.84
Cholecystokinin receptor type A	Cckar	unknown	IC50 6.22

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1974-07-26	FDA	—	—

ATC classification

ATC code	Therapeutic hierarchy
V04CG04	VARIOUS › DIAGNOSTIC AGENTS › OTHER DIAGNOSTIC AGENTS › Tests for gastric secretion

Chemical structure

• Molecular formula: C₃₇H₄₉N₇O₉S
• Molecular weight: 767.90 g/mol
• CAS number: 5534-95-2
• InChIKey: NEYNJQRKHLUJRU-DZUOILHNSA-N
• PubChem CID: 9853654

CSCC[C@H](NC(=O)[C@H](CC1=CNC2=C1C=CC=C2)NC(=O)CCNC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Pentagastrin work?

Its molecular targets in DrugCentral include Cckbr, Cckbr, CCKBR and Cckar.

When was Pentagastrin first approved?

Pentagastrin was first approved by the FDA in 1974.

What is the chemical formula of Pentagastrin?

Pentagastrin has the molecular formula C37H49N7O9S and a molecular weight of 767.90 g/mol.

Sources

• DrugCentral drug card 2088 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1328 — compound record and bioactivity
• PubChem CID 9853654 — chemical identifiers
• DrugBank DB00183 — drug record
• FDA UNII EF0NX91490 — substance identity
• DailyMed: FDA labels for Pentagastrin — current prescribing information (label search)
• UniProt P32239 (CCKBR) — target protein

How this page is built: methodology · editorial policy & corrections.