Prazepam

NERVOUS SYSTEM

Key facts

Prazepam is an ofm drug catalogued in DrugCentral. DrugCentral lists 1 molecular target, including GABRA1|GABRG2|GABRB2. Recorded indications include Anxiety and Insomnia.

• Approval status: ofm.
• Molecular targets: GABRA1|GABRG2|GABRB2 (1 listed in DrugCentral).
• Indications: Anxiety and Insomnia.
• ATC code: N05BA11 (Benzodiazepine derivatives).
• Molecular formula: C19H17ClN2O; molecular weight 324.81 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (2)

• Anxiety
• Insomnia

Contraindications (18)

• Alcohol intoxication
• Behavioral Disorders
• Borderline personality disorder
• Coma
• Decreased respiratory function
• Depressive disorder
• Disease of liver
• Disorder of lung
• Hypoalbuminemia
• Kidney disease
• Porphyria
• Pregnancy, function
• Psychotic disorder
• Shock
• Sleep apnea
• Sleep automatism
• Substance abuse
• Suicidal thoughts

Mechanism & targets

Molecular targets (1)

Target	Gene	Action	Activity
GABA-A receptor alpha-1/beta-2/gamma-2	GABRA1|GABRG2|GABRB2	positive allosteric modulator	—

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
—	FDA	—	PARKE DAVIS

ATC classification

ATC code	Therapeutic hierarchy
N05BA11	NERVOUS SYSTEM › PSYCHOLEPTICS › ANXIOLYTICS › Benzodiazepine derivatives

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Coma	810.9
Poisoning deliberate	611.7
Somnolence	399.1
Drug abuse	335.5
Miosis	260.3
Drug use disorder	220.3
Intentional overdose	216.5
Altered state of consciousness	186.6
Suicide attempt	164.1
Toxicity to various agents	161.8
Drug dependence	144.0
Mydriasis	127.9

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Prazepam is on its molecule page.

• Molecular formula: C₁₉H₁₇ClN₂O
• Molecular weight: 324.81 g/mol
• CAS number: —
• InChIKey: MWQCHHACWWAQLJ-UHFFFAOYSA-N
• PubChem CID: 4890

ClC1=CC=C2N(CC3CC3)C(=O)CN=C(C3=CC=CC=C3)C2=C1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Prazepam used for?

DrugCentral lists the following indications for Prazepam: Anxiety and Insomnia.

How does Prazepam work?

Its molecular targets in DrugCentral include GABRA1|GABRG2|GABRB2 (positive allosteric modulator).

What is the chemical formula of Prazepam?

Prazepam has the molecular formula C19H17ClN2O and a molecular weight of 324.81 g/mol.

Sources

• DrugCentral drug card 2240 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL969 — compound record and bioactivity
• PubChem CID 4890 — chemical identifiers
• DrugBank DB01588 — drug record
• FDA UNII Q30VCC064M — substance identity
• DailyMed: FDA labels for Prazepam — current prescribing information (label search)
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

How this page is built: methodology · editorial policy & corrections.