Quinethazone

CARDIOVASCULAR SYSTEM

Key facts

Quinethazone is an ofm drug catalogued in DrugCentral. It was first approved by the FDA in 1963. DrugCentral lists 1 molecular target, including SLC12A3.

• Approval status: ofm (first approved 1963 by the FDA).
• Molecular targets: SLC12A3 (1 listed in DrugCentral).
• ATC code: C03BA02 (Sulfonamides, plain).
• Molecular formula: C10H12ClN3O3S; molecular weight 289.74 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Contraindications (11)

• Calculus in biliary tract
• Chronic disease of respiratory system
• Chronic heart failure
• Conduction disorder of the heart
• Depressive disorder
• Electroconvulsive therapy
• Epilepsy
• Kidney disease
• Peptic ulcer
• Suicidal thoughts
• Ulcerative colitis

Mechanism & targets

Molecular targets (1)

Target	Gene	Action	Activity
Solute carrier family 12 member 3	SLC12A3	inhibitor	—

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1963-04-10	FDA	—	—

ATC classification

ATC code	Therapeutic hierarchy
C03BA02	CARDIOVASCULAR SYSTEM › DIURETICS › LOW-CEILING DIURETICS, EXCL. THIAZIDES › Sulfonamides, plain
C03BB02	CARDIOVASCULAR SYSTEM › DIURETICS › LOW-CEILING DIURETICS, EXCL. THIAZIDES › Sulfonamides and potassium in combination

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Quinethazone is on its molecule page.

• Molecular formula: C₁₀H₁₂ClN₃O₃S
• Molecular weight: 289.74 g/mol
• CAS number: —
• InChIKey: AGMMTXLNIQSRCG-UHFFFAOYSA-N
• PubChem CID: 6307

CCC1NC(=O)C2=CC(=C(Cl)C=C2N1)S(N)(=O)=O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Quinethazone work?

Its molecular targets in DrugCentral include SLC12A3 (inhibitor).

When was Quinethazone first approved?

Quinethazone was first approved by the FDA in 1963.

What is the chemical formula of Quinethazone?

Quinethazone has the molecular formula C10H12ClN3O3S and a molecular weight of 289.74 g/mol.

Sources

• DrugCentral drug card 2343 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1532 — compound record and bioactivity
• PubChem CID 6307 — chemical identifiers
• DrugBank DB01325 — drug record
• FDA UNII 455E0S048W — substance identity
• DailyMed: FDA labels for Quinethazone — current prescribing information (label search)
• UniProt P55017 (SLC12A3) — target protein

How this page is built: methodology · editorial policy & corrections.